I also drank an ensure every day the week of chemothat does give you a boost. The interval between each treatment gives your body time to recover. We can get through it! Of course, we each respond as individuals. The problem some people run into with Taxotere is that the hair loss can sometimes be permanent. When working in your yard, wear protective clothing including long pants and gloves. Yes you will have have to have the G - CSFinjections for the bone marrow stimulation after the Docetaxal chemotherapy - the same as the FEC. Docetaxel interferes with the function of microtubules, resulting in inactive microtubule bundles, causing cells to die. And yes, for me at least, it is cumulative and is a bit worse each cycle. You will have got through it now though? A week later, I would have another dose of Gemcitabine and an hour of Taxotere. The cycles were repeated every 3 weeks for 3 . Fatigue is very common as a side effect. as these can all increase the risk of bleeding. My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. Days 1 & 7, I was tired but could function to some degree - I made it to infusions. It won't be long until you to are in a position to help others with your experiences of the journey we all find ourselves on. Thanks everyone for your messages of support. constipation. Thank you, i hope your recovery continues to bring good news and health. Tax is bad, next time compounded it might be worse, roll on July! My next 2 cycles went ok so, hopefully you are through the worst. I have a good support system at home who do just about everything as I have been bed or sofa bound for the last 10 days with just small walks around the house to keep the circulation going. That finished months ago, but she's still whacked by the docetaxel on and off. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. Your fingernails/toenails may become dark, brittle or fall off. Hi, You may use nail polish, but do not wear fake nails. You may also feel irritable, dizzy, or short of breath. Sorry for the extended message but reading these chats means I'm not alone and I'm not a hypochondriac (as believe me I've thought it) Certain cancer treatments can cause sores or soreness in your mouth and/or throat. xoxoxoxo Lynn. The mouth issues I suffered with all the way through chemo (didn't have thrush) but would say the mouth part was my worst SE. Shari S. (Breast Cancer, Invasive Ductal Carcinoma (IDC),Triple Positive, Stage 4). For some people, it never completely goes away. You should not breastfeed while receiving this medication or for 1 week after your last dose. All patients should be premedicated with oral corticosteroids (see below for prostate cancer) such as dexamethasone 16 mg per day (e.g., 8 mg twice daily) for 3 days starting 1 day prior to TAXOTERE administration in order to reduce the incidence and severity of fluid retention as well as the severity of hypersensitivity reactions [see Boxed Warning, Warnings and . Your nurse will check you for signs of a reaction during your treatment. If you notice any changes in how you feel during the infusion, let your nurse know immediately. It takes the edge off the pain which means taking paracetamol with it actually works. An absolute pleasure to have helped. I don't know about AC, but when I was on TC, I was told that it's not cumulative, so I would not be feeling worse as chemo progressed.Good luck to Donna, I hope she gets the rest she needs. worst daysfor me it was the week after the infusion..I just fall apart.tired, ache, intestinal issuesetc. Painkillers, she had all the same things as you. I followed all the advice and recommendations given by the medical team and tried to be positive about the treatment working to fight the cancer but it has been hard. Even if it is to moan. Avoid any food that you think smells or tastes bad. If the count gets too low, you may receive a blood transfusion. Thats Taxotere and Cyclophosphamide. (And day 12 after my third and final Tax - I'd probably still say the same. Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. Premedication is required with Docetaxel. Your Wife is unique! Laughter is fast-acting, too. After starting docetaxel, many men experience the improvements in disease-related symptoms, including pain, fatigue and loss of energy. A week in hospital on IV antibiotics and fluids and I was allowed home to rest rest rest! I have finished 4 cycles so far with 4 more to go. It is used as a treatment for various cancers, most notably breast cancer. Take care and we will get through this. My skin, when I rub my fingers or touch my face, arms, legs etc feels different, almost plastic-y! xx, My consultant reduced my injection strength so I had to endure 10 injections as prescribed. Scared to the point of not being able to sleep properly. For obvious reasons, Saturday is the best day of the week because it's a holiday and the next day too is a holiday, followed by Friday because it's preceded by two holidays. You have given me some great pointers and hopefully I can be calmer about my next 2 cycles. Gone too far now to stop just need to finish the course. I'm fortunate in that my husband is self employed. Your red blood cells are responsible for carrying oxygen to the tissues in your body. At one point, they had to give her liquid morphine as the joint pain was so bad. worst: [adverb] to the extreme degree of badness or inferiority. Try some meditation (use an app if you don't have any). Make sure that those around you understand that while the pain peaks, you need absolute rest. While we were driving home - it's a nice, sunny, fairly warm day - Moopy observed that getting out was a reminder of what our life will be like again. The steroid is given in pill form or by IV, which will be determined by your healthcare provider. Genoa M. (Breast Cancer, Invasive Ductal Carcinoma [IDC], Stage 3, HER2+). Thank you for sharing your journey and giving me hope. DelveInsight has compiled the symposium's major highlights so that one does not miss out on these expansions . Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. Peripheral neuropathy is a toxicity that affects the nerves. I have the district nurse for the 5 injections following chemo and also the Picc line flushes as not left the house since last chemo, not had the energy. This typically begins two to three weeks after treatment starts. I do have to rest far more than I used to, although I manage to cope with a busy full time job. pathology report has our Onc ordering additional scans. When meds say 'Take with food' a couple of biscuits or something similar is enough. Fatigue is very common during cancer treatment and is an overwhelming feeling of exhaustion that is not usually relieved by rest. At least week three is getting close, mine starts next Tuesday. For your mouth get som kingingical mouth wash and rinse with salt water every hour or so. These symptoms can last for several months or longer after treatment ends. Treatment . The Doctor informed me it is normal to experience these problems but they should not have continued for so long. Taxotere injections can cause your white blood cell levels to plummet. I know everyone is different. Try to eat five or six small meals or snacks throughout the day, instead of 3 larger meals. None worked. TAXOTERE (docetaxel) Injection Concentrate is a clear yellow to brownish-yellow viscous solution. Avoid contact sports and activities that can result in injury or bleeding. Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. All that said, she was down for a mastectomy too, except, the docetaxel absolutely obliterated the cancer. We needed to make a spread sheet of what pills to take and when. Hopefully this will work out and spare me the ordeal of last time. x, Dolbycat,I was exactly like you,I couldn't eat and was constantly retching at the sight or smell of food,and was also bad with aches like you,sorry to say the eating thing didn't get any easier during my 4 cycles of docetaxl but the aches got easier with the help of ibuprofen and paracetomol but you have to be vigilant and take them regular basis.I would say just make some nutritional soups and eat them but don't expect to enjoy your food for a while.Just resign yourself to the fact that you need to have the poison to kill the cancer and you have to take food even if you can't face it.It does end,I know how you feel,I was exactly the same ,felt like giving up.Ask for plenty of help and keep drinking water.Stay strong,luv Vicky.x, Thank you for helping me to understand. That's really great that she had that positive response though, seems worth it and hopeful for the rest of us! Sore throat, swallowing, that was usually first couple of days then I started using Biotene (mouthwash)the day before chemo, the day of chemo, and the day after, and I didnt have any issues with that after at all. Search deep within yourself, you will find the strength. The U.S. Food and Drug Administration originally approved the drug in 1996. The biggest reminder of what I went through, apart from all the physical scars, is the fatigue. Paracetamol Ibuprofen/codiene didn't work. Youre coming back off. It helps with pain so uncomfortable in spasms but endurable if I dont climb too many stairs with lead legs, It may have helped the mouth too, the stronger dose did make me reach for the bonjella where moments before was ok. 10 days of horrible tastes and softer foods has been hard. So my advice is dont be scared to ring the chemo hotline, they know what to advise and whether or not you should go in.. What Is the Taxotere Mechanism of Action? 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